|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Mass |
Formula |
Description |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
18.0104 |
89.0112 |
90.047 |
135.032 |
147.1048 |
1 |
3 |
4 |
5 |
2 |
1 |
|
77 |
|
|
|
-90.0470 |
-C7H6 |
Benzyl loss |
|
|
|
|
|
|
|
|
|
|
|
|
|
Relative |
Neutralized |
Sum of |
|
|
|
|
|
|
|
0 |
0 |
0 |
0 |
0 |
1 |
3 |
5 |
4 |
2 |
59 |
|
2 |
|
|
|
-56.0626 |
-C4H8 |
Loss of butylene |
|
|
|
|
|
|
|
|
|
|
|
|
|
Intensities |
Fragment Masses |
Subfragments |
|
|
|
|
|
|
|
0 |
89.0112 |
90.047 |
135.032 |
0 |
1 |
5 |
3 |
4 |
2 |
|
|
2 |
|
|
|
-43.9495 |
Br -> Cl |
Bromine to chlorine |
|
|
|
|
|
|
|
|
|
|
|
|
|
100 |
90.0470 |
90.0470 |
|
|
|
|
|
|
|
0 |
0 |
0 |
0 |
0 |
1 |
5 |
4 |
3 |
2 |
|
|
2 |
|
|
|
-42.0470 |
-C3H6 |
Depropylation |
|
|
|
|
|
|
|
|
|
|
|
|
|
29 |
147.1048 |
147.1048 |
|
|
|
|
|
|
|
0 |
0 |
0 |
0 |
0 |
3 |
1 |
2 |
4 |
5 |
|
|
3 |
|
|
|
-42.0106 |
-C2H2O |
Deacetylation |
|
|
|
|
|
|
|
|
|
|
|
|
|
9 |
165.1154 |
165.1152 |
|
|
|
|
|
|
|
0 |
0 |
0 |
0 |
0 |
3 |
1 |
4 |
2 |
5 |
|
|
3 |
|
|
|
-29.9742 |
NO2 -> NH2 |
N-reduction (nitro group) |
|
|
|
|
|
|
|
|
|
|
|
|
|
10 |
225.0790 |
225.0790 |
|
|
|
|
|
|
|
0 |
0 |
0 |
0 |
0 |
4 |
1 |
2 |
3 |
5 |
|
|
2 |
|
|
|
-28.0313 |
-C2H4 |
loss of ethylene |
|
|
|
|
|
|
|
|
|
|
|
|
|
8 |
267.0896 |
0.0000 |
|
|
|
|
|
|
|
0 |
0 |
0 |
0 |
0 |
4 |
1 |
3 |
2 |
5 |
|
|
2 |
|
|
|
-17.9661 |
Cl -> OH |
substitution of OH for Cl |
|
|
|
|
|
|
|
|
|
|
|
|
|
17 |
268.0975 |
0.0000 |
|
|
|
|
|
|
|
0 |
0 |
90.047 |
135.032 |
0 |
4 |
3 |
1 |
2 |
5 |
|
|
2 |
|
|
|
-15.9949 |
-O |
Reduction |
|
|
|
|
|
|
|
|
|
|
|
|
|
10 |
282.0640 |
0.0000 |
|
|
|
|
|
|
|
18.0104 |
0 |
0 |
0 |
147.1048 |
4 |
3 |
2 |
1 |
5 |
|
|
2 |
|
|
|
-14.0157 |
-CH2 |
Demethylation |
|
|
|
|
|
|
|
|
|
|
|
|
|
12 |
297.0877 |
0.0000 |
|
|
|
|
|
|
|
0 |
0 |
0 |
0 |
147.1048 |
|
|
|
|
|
|
|
|
|
|
|
-2.0157 |
-H2 |
Dehydrogenation |
|
|
|
|
|
|
|
|
|
|
|
|
|
9 |
300.0873 |
0.0000 |
|
|
|
|
|
|
|
0 |
0 |
90.047 |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
-1.0316 |
CH4N -> CHO |
Oxidative Deamination |
|
|
|
|
|
|
|
|
|
|
|
|
|
45 |
314.0903 |
314.0902 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2.0157 |
+H2 |
Hydrogenation |
|
|
|
|
|
|
|
|
|
|
|
|
|
15 |
358.1166 |
0.0000 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
4.0313 |
+2H2 |
2x Hydrogenation |
|
|
|
|
|
|
|
|
|
|
|
|
|
0 |
479.2056 |
479.2054 |
|
|
|
|
|
|
|
H2O |
C2H3NO3 |
C7H6 |
C7H5NO2 |
C10H13N |
|
|
|
|
|
C26H29N3O6 |
0.06 |
300 |
|
|
13.9793 |
CH2OH -> COOH |
Oxidation of alcohols |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
H2O |
C2H3NO3 |
C4H7OF |
C7H5NO2 |
C10H13N |
|
|
|
|
|
C23H30N3O7F |
0.27 |
68 |
|
|
14.0157 |
+CH2 |
Methylation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
H2O |
C2H3NO3 |
C7H6 |
C7H5NO2 |
C7H14NOF |
|
|
|
|
C23H30N3O7F |
0.30 |
60 |
|
|
15.9949 |
+O |
Oxidation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
H2O |
C2H3NO3 |
C2H5N3F |
C7H5NO2 |
C5H12N4F |
|
|
|
|
C16H27N9O6F2 |
0.11 |
48 |
|
|
18.0106 |
+H2O |
Hydrolysis of cyclic amides and esters |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Alignment of SubFragments |
|
|
H2O |
C5HN2 |
C7H6 |
C7H5NO2 |
C7H15O3 |
|
|
|
|
|
C26H29N3O6 |
1.15 |
43 |
|
|
27.9949 |
RNH2 -> RNH-HC=O |
Formylation (DMF solvent) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
SubFrag 1 |
SubFrag 2 |
SubFrag 3 |
SubFrag 4 |
SubFrag 5 |
|
|
H2O |
C5HN2 |
C7H6 |
C5H3N4O |
C10H13N |
|
|
|
|
|
C27H25N7O2 |
0.85 |
41 |
|
|
28.0313 |
+C2H4 |
addition of ethyl |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
S |
|
H2O |
C2H3NO3 |
C4H7OF |
C7H5NO2 |
C7H14NOF |
|
|
|
|
C20H31N3O8F2 |
0.51 |
36 |
|
|
29.9742 |
CH3 -> COOH |
Methyl group oxidation to acid |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
18.0104 |
147.1048 |
89.0112 |
90.0470 |
135.0320 |
479 |
|
H2O |
C2H3NO3 |
C7H6 |
C3H8N2O2P |
C5H12N4F |
|
|
|
|
C17H31N7O6PF |
0.16 |
32 |
|
|
31.9898 |
+O2 |
2x Oxidation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0 |
|
H2O |
C2H3NO3 |
C2H5N3F |
C3H8N2O2P |
C10H13N |
|
|
|
|
|
C17H31N7O6PF |
0.16 |
31 |
|
|
42.0106 |
+C2H2O |
Acetylation (DMAc solvent) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Partition
Score |
|
0.0000 |
0.0000 |
89.0112 |
90.0470 |
135.0320 |
314 |
|
H2O |
C2H3NO3 |
C7H6 |
C5H4NF3 |
C10H13N |
|
|
|
|
|
C24H28N3O4F3 |
0.53 |
30 |
|
|
42.0470 |
+C3H6 |
addition of a propyl group |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0 |
|
H2O |
C2H3NO3 |
C4H7OF |
C5H4NF3 |
C10H13N |
|
|
|
|
|
C21H29N3O5F4 |
0.74 |
22 |
|
|
43.9495 |
Cl -> Br |
Chlorine to Bromine substitution |
|
|
|
|
|
|
|
|
|
|
|
|
|
57 |
|
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0 |
|
H2O |
C5HN2 |
C7H6 |
C5H3N4O |
C7H14NOF |
|
|
|
|
C24H26N7O3F |
1.09 |
21 |
|
|
57.0215 |
C2H3NO |
Glycine conjugate formation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0 |
|
H2O |
C2H3NO3 |
C7H6 |
C5H4NF3 |
C7H14NOF |
|
|
|
|
C21H29N3O5F4 |
0.77 |
21 |
|
|
69.0578 |
OH -> C4H8NO |
amidation with
morpholine (NMM solvent) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0 |
|
H2O |
C5HN2 |
C4H7OF |
C5H3N4O |
C10H13N |
|
|
|
|
|
C24H26N7O3F |
1.06 |
19 |
|
|
79.9568 |
+SO3 |
Sulfate ester formation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0.0000 |
0 |
|
H2O |
C2H3NO3 |
C7H6 |
C5H3N4O |
C5H12N4F |
|
|
|
|
C19H26N9O5F |
0.32 |
19 |
|
|
79.9663 |
+PO3H |
Phosphate ester formation |
|
|
|
|
|
|
|
|
|
|
|
|
|
subfragments |
5 |
|
0.0000 |
0.0000 |
0.0000 |
90.0470 |
135.0320 |
225 |
|
H2O |
C5HN2 |
C7H6 |
C5H11S2 |
C10H13N |
|
|
|
|
|
C27H33N3OS2 |
0.95 |
18 |
|
|
86.0368 |
+C4H6O2 |
butyrolactone addition (NMP solvent) |
|
|
|
|
|
|
|
|
|
|
|
|
|
partition number |
5 |
|
18.0104 |
147.1048 |
0.0000 |
0.0000 |
0.0000 |
165 |
|
H2O |
C5HN2 |
C7H6 |
C4H7O5 |
C10H13N |
|
|
|
|
|
C26H29N3O6 |
1.15 |
17 |
|
|
90.0470 |
C7H6 |
Benzyl group addition |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.0000 |
147.1048 |
0.0000 |
0.0000 |
0.0000 |
147 |
|
H2O |
C2H3NO3 |
C4H7OF |
C5H3N4O |
C7H15O3 |
|
|
|
|
|
C18H30N5O9F |
1.05 |
17 |
|
|
107.0041 |
+C2H5NO2S |
Taurine Conjugation |
|
|
|
|
|
|
|
|
|
|
|
|
|
dispersion |
106 |
|
0.0000 |
0.0000 |
0.0000 |
90.0470 |
0.0000 |
90 |
|
H2O |
C2H3NO3 |
C4H7OF |
C5H4NF3 |
C7H14NOF |
|
|
|
|
C18H30N3O6F5 |
0.98 |
16 |
|
|
162.0164 |
+C5H6O6 |
Demethylation + Glucuronidation |
|
|
|
|
|
|
|
|
|
|
|
|
|
Isotope
Ratios |
Avg SubFrag MassError |
Relative Feasibility |
Many Alignments Possible |
|
|
H2O |
C2H3NO3 |
C2H5N3F |
C5H3N4O |
C10H13N |
|
|
|
|
|
C19H26N9O5F |
0.32 |
15 |
|
|
163.0303 |
+C5H9NO3S |
Acetylcysteine addition |
|
|
|
|
|
|
|
|
|
|
|
|
|
100 30
6 1 |
|
|
|
|
|
|
|
|
|
H2O |
C5HN2 |
C4H7OF |
C7H5NO2 |
C7H15O3 |
|
|
|
|
|
C23H30N3O7F |
1.36 |
15 |
|
|
176.0321 |
+C6H8O6 |
Glucuronidation |
|
|
|
|
|
|
|
|
|
|
|
|
|
100 30
5 1 |
0.06 |
300 |
H2O |
C10H13N |
C2H3NO3 |
C7H6 |
C7H5NO2 |
C26H29N3O6 |
|
H2O |
C5HN2 |
C4H7OF |
C4H7O5 |
C10H13N |
|
|
|
|
|
C23H30N3O7F |
1.36 |
15 |
|
|
192.0270 |
+C6H8O7 |
Oxidation + Glucuronidation |
|
|
|
|
|
|
|
|
|
|
|
|
|
100 27
5 1 |
0.27 |
68 |
H2O |
C10H13N |
C2H3NO3 |
C4H7OF |
C7H5NO2 |
C23H30N3O7F |
|
H2O |
C5HN2 |
C4H7OF |
C5H11S2 |
C10H13N |
|
|
|
|
|
C24H34N3O2S2F |
1.15 |
15 |
|
|
307.0838 |
+C10H17N3O6S |
Glutathione addition |
|
|
|
|
|
|
|
|
|
|
|
|
|
100 27
5 1 |
0.30 |
60 |
H2O |
C7H14NOF |
C2H3NO3 |
C7H6 |
C7H5NO2 |
C23H30N3O7F |
|
H2O |
C2H3NO3 |
C4H7OF |
C5H11S2 |
C7H15O3 |
|
|
|
|
|
C18H38NO8S2F |
1.15 |
15 |
|
|
323.0787 |
+C10H17N3O7S |
Oxidation + Glutathione addition |
|
|
|
|
|
|
|
|
|
|
|
|
|
100 21
3 0 |
0.11 |
48 |
H2O |
C5H12N4F |
C2H3NO3 |
C2H5N3F |
C7H5NO2 |
C16H27N9O6F2 |
|
H2O |
C5HN2 |
C7H6 |
C4H7O5 |
C7H14NOF |
|
|
|
|
C23H30N3O7F |
1.39 |
14 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 30
6 1 |
1.15 |
43 |
H2O |
C7H15O3 |
C5HN2 |
C7H6 |
C7H5NO2 |
C26H29N3O6 |
|
H2O |
C5HN2 |
C7H6 |
C5H11S2 |
C7H14NOF |
|
|
|
|
C24H34N3O2S2F |
1.19 |
14 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 32
5 1 |
0.85 |
41 |
H2O |
C10H13N |
C5HN2 |
C7H6 |
C5H3N4O |
C27H25N7O2 |
|
H2O |
C2H3NO3 |
C7H6 |
C5H11S2 |
C5H12N4F |
|
|
|
|
C19H34N5O4S2F |
0.42 |
14 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 23
4 1 |
0.51 |
36 |
H2O |
C7H14NOF |
C2H3NO3 |
C4H7OF |
C7H5NO2 |
C20H31N3O8F2 |
|
H2O |
C5HN2 |
C4H7OF |
C4H7O5 |
C7H14NOF |
|
|
|
|
C20H31N3O8F2 |
1.60 |
13 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
3 0 |
0.16 |
32 |
H2O |
C5H12N4F |
C2H3NO3 |
C7H6 |
C3H8N2O2P |
C17H31N7O6PF |
|
H2O |
C2H3NO3 |
C7H6 |
C2H7N4OS |
C5H12N4F |
|
|
|
|
C16H30N9O5SF |
0.51 |
12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 21
3 0 |
0.16 |
31 |
H2O |
C10H13N |
C2H3NO3 |
C2H5N3F |
C3H8N2O2P |
C17H31N7O6PF |
|
H2O |
C2H3NO3 |
C2H5N3F |
C5H11S2 |
C10H13N |
|
|
|
|
|
C19H34N5O4S2F |
0.42 |
12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 28
4 1 |
0.53 |
30 |
H2O |
C10H13N |
C2H3NO3 |
C7H6 |
C5H4NF3 |
C24H28N3O4F3 |
|
H2O |
C5HN2 |
C4H7OF |
C5H11S2 |
C7H14NOF |
|
|
|
|
C21H35N3O3S2F2 |
1.39 |
12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 24
4 0 |
0.74 |
22 |
H2O |
C10H13N |
C2H3NO3 |
C4H7OF |
C5H4NF3 |
C21H29N3O5F4 |
|
H2O |
C2H3NO3 |
C4H7OF |
C5H3N4O |
C5H12N4F |
|
|
|
|
C16H27N9O6F2 |
0.53 |
11 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 29
5 1 |
1.09 |
21 |
H2O |
C7H14NOF |
C5HN2 |
C7H6 |
C5H3N4O |
C24H26N7O3F |
|
H2O |
C5HN2 |
C7H6 |
C7H5NO2 |
C5H12N4F |
|
|
|
|
C24H26N7O3F |
0.63 |
10 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 24
4 0 |
0.77 |
21 |
H2O |
C7H14NOF |
C2H3NO3 |
C7H6 |
C5H4NF3 |
C21H29N3O5F4 |
|
H2O |
C2H3NO3 |
C7H6 |
C4H7O5 |
C5H12N4F |
|
|
|
|
C18H30N5O9F |
0.62 |
10 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 29
5 1 |
1.06 |
19 |
H2O |
C10H13N |
C5HN2 |
C4H7OF |
C5H3N4O |
C24H26N7O3F |
|
H2O |
C2H3NO3 |
C2H5N3F |
C2H7N4OS |
C10H13N |
|
|
|
|
|
C16H30N9O5SF |
0.52 |
10 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 24
4 0 |
0.32 |
19 |
H2O |
C5H12N4F |
C2H3NO3 |
C7H6 |
C5H3N4O |
C19H26N9O5F |
|
H2O |
C2H3NO3 |
C4H7OF |
C5H11S2 |
C5H12N4F |
|
|
|
|
C16H35N5O5S2F2 |
0.63 |
10 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 32
14 3 |
0.95 |
18 |
H2O |
C10H13N |
C5HN2 |
C7H6 |
C5H11S2 |
C27H33N3OS2 |
|
H2O |
C5HN2 |
C7H6 |
C5H4NF3 |
C7H15O3 |
|
|
|
|
|
C24H28N3O4F3 |
1.62 |
10 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 29
6 1 |
1.15 |
17 |
H2O |
C10H13N |
C5HN2 |
C7H6 |
C4H7O5 |
C26H29N3O6 |
|
H2O |
C2H3NO3 |
C2H5N3F |
C5H3N4O |
C7H14NOF |
|
|
|
|
C16H27N9O6F2 |
0.56 |
9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
4 1 |
1.05 |
17 |
H2O |
C7H15O3 |
C2H3NO3 |
C4H7OF |
C5H3N4O |
C18H30N5O9F |
|
H2O |
C5HN2 |
C4H7OF |
C5H4NF3 |
C7H15O3 |
|
|
|
|
|
C21H29N3O5F4 |
1.83 |
9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 21
3 0 |
0.98 |
16 |
H2O |
C7H14NOF |
C2H3NO3 |
C4H7OF |
C5H4NF3 |
C18H30N3O6F5 |
|
H2O |
C5HN2 |
C2H5N3F |
C7H5NO2 |
C10H13N |
|
|
|
|
|
C24H26N7O3F |
0.64 |
8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 24
4 0 |
0.32 |
15 |
H2O |
C10H13N |
C2H3NO3 |
C2H5N3F |
C5H3N4O |
C19H26N9O5F |
|
H2O |
C2H3NO3 |
C2H5N3F |
C7H5NO2 |
C7H15O3 |
|
|
|
|
|
C18H30N5O9F |
0.63 |
8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 27
5 1 |
1.36 |
15 |
H2O |
C7H15O3 |
C5HN2 |
C4H7OF |
C7H5NO2 |
C23H30N3O7F |
|
H2O |
C2H3NO3 |
C2H5N3F |
C4H7O5 |
C10H13N |
|
|
|
|
|
C18H30N5O9F |
0.62 |
8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 26
5 1 |
1.36 |
15 |
H2O |
C10H13N |
C5HN2 |
C4H7OF |
C4H7O5 |
C23H30N3O7F |
|
H2O |
C2H3NO3 |
C2H5N3F |
C5H11S2 |
C7H14NOF |
|
|
|
|
C16H35N5O5S2F2 |
0.66 |
8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 29
13 3 |
1.15 |
15 |
H2O |
C10H13N |
C5HN2 |
C4H7OF |
C5H11S2 |
C24H34N3O2S2F |
|
H2O |
C2H3NO3 |
C7H6 |
C2H7N4OS |
C7H15O3 |
|
|
|
|
|
C18H33N5O8S |
1.03 |
7 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
13 2 |
1.15 |
15 |
H2O |
C7H15O3 |
C2H3NO3 |
C4H7OF |
C5H11S2 |
C18H38NO8S2F |
|
H2O |
C5HN2 |
C7H6 |
C3H8N2O2P |
C10H13N |
|
|
|
|
|
C25H30N5O3P |
0.69 |
7 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 26
5 1 |
1.39 |
14 |
H2O |
C7H14NOF |
C5HN2 |
C7H6 |
C4H7O5 |
C23H30N3O7F |
|
H2O |
C2H3NO3 |
C7H6 |
C3H8N2O2P |
C7H15O3 |
|
|
|
|
|
C19H34N3O9P |
0.68 |
7 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 29
13 3 |
1.19 |
14 |
H2O |
C7H14NOF |
C5HN2 |
C7H6 |
C5H11S2 |
C24H34N3O2S2F |
|
H2O |
C5HN2 |
C2H5N3F |
C3H8N2O2P |
C5H12N4F |
|
|
|
|
C15H28N11O3PF2 |
0.73 |
7 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 24
13 3 |
0.42 |
14 |
H2O |
C5H12N4F |
C2H3NO3 |
C7H6 |
C5H11S2 |
C19H34N5O4S2F |
|
H2O |
C5HN2 |
C2H5N3F |
C5H3N4O |
C5H12N4F |
|
|
|
|
C17H23N13O2F2 |
0.89 |
6 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 23
4 1 |
1.60 |
13 |
H2O |
C7H14NOF |
C5HN2 |
C4H7OF |
C4H7O5 |
C20H31N3O8F2 |
|
H2O |
C5HN2 |
C2H5N3F |
C5H11S2 |
C5H12N4F |
|
|
|
|
C17H31N9OS2F2 |
0.99 |
5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
8 1 |
0.51 |
12 |
H2O |
C5H12N4F |
C2H3NO3 |
C7H6 |
C2H7N4OS |
C16H30N9O5SF |
|
H2O |
C5HN2 |
C7H6 |
C5H4NF3 |
C5H12N4F |
|
|
|
|
C22H25N7OF4 |
1.10 |
5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 25
13 3 |
0.42 |
12 |
H2O |
C10H13N |
C2H3NO3 |
C2H5N3F |
C5H11S2 |
C19H34N5O4S2F |
|
H2O |
C5HN2 |
C2H5N3F |
C5H4NF3 |
C10H13N |
|
|
|
|
|
C22H25N7OF4 |
1.11 |
5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 26
13 3 |
1.39 |
12 |
H2O |
C7H14NOF |
C5HN2 |
C4H7OF |
C5H11S2 |
C21H35N3O3S2F2 |
|
H2O |
C5HN2 |
C4H7OF |
C5H4NF3 |
C5H12N4F |
|
|
|
|
C19H26N7O2F5 |
1.31 |
5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 21
3 0 |
0.53 |
11 |
H2O |
C5H12N4F |
C2H3NO3 |
C4H7OF |
C5H3N4O |
C16H27N9O6F2 |
|
H2O |
C5HN2 |
C2H5N3F |
C5H3N4O |
C7H15O3 |
|
|
|
|
|
C19H26N9O5F |
1.41 |
4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 29
5 1 |
0.63 |
10 |
H2O |
C5H12N4F |
C5HN2 |
C7H6 |
C7H5NO2 |
C24H26N7O3F |
|
H2O |
C5HN2 |
C2H5N3F |
C3H8N2O2P |
C7H15O3 |
|
|
|
|
|
C17H31N7O6PF |
1.25 |
4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
4 1 |
0.62 |
10 |
H2O |
C5H12N4F |
C2H3NO3 |
C7H6 |
C4H7O5 |
C18H30N5O9F |
|
H2O |
C5HN2 |
C2H5N3F |
C4H7O5 |
C5H12N4F |
|
|
|
|
C16H27N9O6F2 |
1.19 |
4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
8 1 |
0.52 |
10 |
H2O |
C10H13N |
C2H3NO3 |
C2H5N3F |
C2H7N4OS |
C16H30N9O5SF |
|
H2O |
C5HN2 |
C2H5N3F |
C5H4NF3 |
C7H14NOF |
|
|
|
|
C19H26N7O2F5 |
1.35 |
4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 21
12 2 |
0.63 |
10 |
H2O |
C5H12N4F |
C2H3NO3 |
C4H7OF |
C5H11S2 |
C16H35N5O5S2F2 |
|
H2O |
C5HN2 |
C2H5N3F |
C4H7O5 |
C7H15O3 |
|
|
|
|
|
C18H30N5O9F |
1.71 |
3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 27
4 1 |
1.62 |
10 |
H2O |
C7H15O3 |
C5HN2 |
C7H6 |
C5H4NF3 |
C24H28N3O4F3 |
|
H2O |
C5HN2 |
C2H5N3F |
C2H7N4OS |
C7H15O3 |
|
|
|
|
|
C16H30N9O5SF |
1.61 |
3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 21
3 0 |
0.56 |
9 |
H2O |
C7H14NOF |
C2H3NO3 |
C2H5N3F |
C5H3N4O |
C16H27N9O6F2 |
|
H2O |
C5HN2 |
C2H5N3F |
C5H11S2 |
C7H15O3 |
|
|
|
|
|
C19H34N5O4S2F |
1.51 |
3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 24
4 0 |
1.83 |
9 |
H2O |
C7H15O3 |
C5HN2 |
C4H7OF |
C5H4NF3 |
C21H29N3O5F4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 29
5 1 |
0.64 |
8 |
H2O |
C10H13N |
C5HN2 |
C2H5N3F |
C7H5NO2 |
C24H26N7O3F |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
4 1 |
0.63 |
8 |
H2O |
C7H15O3 |
C2H3NO3 |
C2H5N3F |
C7H5NO2 |
C18H30N5O9F |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
4 1 |
0.62 |
8 |
H2O |
C10H13N |
C2H3NO3 |
C2H5N3F |
C4H7O5 |
C18H30N5O9F |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 21
12 2 |
0.66 |
8 |
H2O |
C7H14NOF |
C2H3NO3 |
C2H5N3F |
C5H11S2 |
C16H35N5O5S2F2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
9 1 |
1.03 |
7 |
H2O |
C7H15O3 |
C2H3NO3 |
C7H6 |
C2H7N4OS |
C18H33N5O8S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 29
5 1 |
0.69 |
7 |
H2O |
C10H13N |
C5HN2 |
C7H6 |
C3H8N2O2P |
C25H30N5O3P |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 22
4 1 |
0.68 |
7 |
H2O |
C7H15O3 |
C2H3NO3 |
C7H6 |
C3H8N2O2P |
C19H34N3O9P |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 21
3 0 |
0.73 |
7 |
H2O |
C5H12N4F |
C5HN2 |
C2H5N3F |
C3H8N2O2P |
C15H28N11O3PF2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 23
3 0 |
0.89 |
6 |
H2O |
C5H12N4F |
C5HN2 |
C2H5N3F |
C5H3N4O |
C17H23N13O2F2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 24
12 2 |
0.99 |
5 |
H2O |
C5H12N4F |
C5HN2 |
C2H5N3F |
C5H11S2 |
C17H31N9OS2F2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 26
4 0 |
1.10 |
5 |
H2O |
C5H12N4F |
C5HN2 |
C7H6 |
C5H4NF3 |
C22H25N7OF4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 27
4 0 |
1.11 |
5 |
H2O |
C10H13N |
C5HN2 |
C2H5N3F |
C5H4NF3 |
C22H25N7OF4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
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|
|
|
|
|
100 24
3 0 |
1.31 |
5 |
H2O |
C5H12N4F |
C5HN2 |
C4H7OF |
C5H4NF3 |
C19H26N7O2F5 |
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100 25
4 0 |
1.41 |
4 |
H2O |
C7H15O3 |
C5HN2 |
C2H5N3F |
C5H3N4O |
C19H26N9O5F |
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100 21
3 0 |
1.25 |
4 |
H2O |
C7H15O3 |
C5HN2 |
C2H5N3F |
C3H8N2O2P |
C17H31N7O6PF |
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100 21
3 0 |
1.19 |
4 |
H2O |
C5H12N4F |
C5HN2 |
C2H5N3F |
C4H7O5 |
C16H27N9O6F2 |
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100 24
3 0 |
1.35 |
4 |
H2O |
C7H14NOF |
C5HN2 |
C2H5N3F |
C5H4NF3 |
C19H26N7O2F5 |
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100 22
4 1 |
1.71 |
3 |
H2O |
C7H15O3 |
C5HN2 |
C2H5N3F |
C4H7O5 |
C18H30N5O9F |
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100 22
8 1 |
1.61 |
3 |
H2O |
C7H15O3 |
C5HN2 |
C2H5N3F |
C2H7N4OS |
C16H30N9O5SF |
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100 25
13 3 |
1.51 |
3 |
H2O |
C7H15O3 |
C5HN2 |
C2H5N3F |
C5H11S2 |
C19H34N5O4S2F |
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